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Insulin R/CD220: Products

Insulin Receptor (INSR, CD220) is a type I transmembrane glycoprotein in the Insulin/IGF Receptor family of receptor tyrosine kinases. The mature receptor contains an extracellular alpha subunit and an extracellular/transmembrane/cytoplasmic beta subunit. Alternative splicing generates A and B isoforms which may homodimerize or heterodimerize with the IGF-I receptor. All receptor combinations bind Insulin, IGF-I, or IGF-II, but with differing affinities. Insulin R signaling regulates glucose uptake and metabolism but also contributes to cell growth, differentiation and apoptosis. Mutations in INSR have been linked to severe insulin resistance (type A and Rabson-Mendenhall syndrome), type II diabetes mellitus, and leprechaunism (Donohue syndrome)

Showing 1-24 out of 24 Insulin R/CD220 Products

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DescriptionApplicationCat#CitationsImages 

Recombinant Human Insulin R/CD220 (aa 28-944) Protein, CF

 1544-IR/CF2  
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Recombinant Human Insulin R/CD220 (aa 28-944) Protein

 1544-IR2  
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Proteome Profiler Human Phospho-RTK Array Kit


Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies
ARY001B96  
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Human Phospho-Insulin R (Y1162/Y1163)/
IGF-I R (Y1135/Y1136) Antibody

Flow, ICC/IF, WBAF25073  
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Human Insulin R/CD220 Antibody

WBMAB15441 
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Recombinant Mouse Insulin R/CD220 Protein, CF

 7544-MR 
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Human/Mouse Insulin R/CD220 PE-conjugated Antibody

FlowFAB1544P1  
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Human/Mouse Insulin R/CD220 APC-conjugated Antibody

FlowFAB1544A1  
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Human/Mouse Insulin R/CD220 Alexa Fluor® 700-conjugated Antibody

FlowFAB1544N 
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Human/Mouse Insulin R/CD220 Alexa Fluor® 488-conjugated Antibody

FlowFAB1544G 
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Human Total Insulin R DuoSet IC ELISA

ELISADYC1544-22  
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Human Insulin R/CD220 Antibody

Flow, IHC, WBAF1544 
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Human Phospho-Insulin R DuoSet IC ELISA

ELISADYC2718-22  
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BMS 536924


Dual IR/IGF1R inhibitor
47741  
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Human Insulin R/CD220 Antibody

Flow, ICC/IFMAB1544 
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Human Insulin R/CD220 Biotinylated Antibody

WBBAF1544 
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NBI 31772


High affinity insulin-like growth factor-I binding protein IGFBP inhibitor
5192 
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GSK 1838705


Potent IR and IGF1R inhibitor; also inhibits anaplastic lymphoma kinase (ALK)
5111 
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Human Insulin R/CD220 (NP_000199) VersaClone cDNA

RDC1239 
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Human Insulin R/CD220 (NP_001073285) VersaClone cDNA

RDC0878 
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Recombinant Human Insulin R/CD220 (aa 28-956) Protein, CF


B Isoform
 8974-IR 
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Human Insulin R/CD220 Biotinylated Antibody

FlowBAM1544 
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Proteome Profiler Mouse Phospho-RTK Array Kit


Contains 4 membranes - each spotted in duplicate with 39 different RTK antibodies
ARY0147  
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Proteome Profiler Human Ubiquitin Array


Contains 4 membranes-each spotted in duplicate with 49 different antibodies to ubiquitin target proteins
ARY027 
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