Insulysin/IDE: Products

Insulysin, or insulin-degrading enzyme (IDE), is a zinc metallopeptidase of the inverzincin family. IDE is primarily located in the cytosol, but has been detected as a secreted enzyme and associated with the plasma membrane as well. The enzyme is expressed in many tissues, with the highest levels in liver, kidney, brain, and testis. IDE hydrolyzes a variety of regulatory peptides, including insulin, glucagon, atrial natriuretic factor, and transforming growth factor-alpha in vitro. In addition, IDE has been shown to degrade the amyloid beta (A beta) peptide, which polymerizes into the plaques associated with Alzheimer's disease.

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Recombinant Human Insulysin/IDE Protein, CF

 2496-ZN3  
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Human Insulysin/IDE Antibody

IP, WBAF24961  
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Human Insulysin/IDE Antibody

Flow, WBMAB2496 
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Recombinant Rat Insulysin/IDE Protein, CF

 6958-ZN 
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