Insulysin/IDE: Products

Insulysin, or insulin-degrading enzyme (IDE), is a zinc metallopeptidase of the inverzincin family. IDE is primarily located in the cytosol, but has been detected as a secreted enzyme and associated with the plasma membrane as well. The enzyme is expressed in many tissues, with the highest levels in liver, kidney, brain, and testis. IDE hydrolyzes a variety of regulatory peptides, including insulin, glucagon, atrial natriuretic factor, and transforming growth factor-alpha in vitro. In addition, IDE has been shown to degrade the amyloid beta (A beta) peptide, which polymerizes into the plaques associated with Alzheimer's disease.

Showing 1-11 out of 11 Insulysin/IDE Products

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Recombinant Human Insulysin/IDE Protein, CF

 2496-ZN4  
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Human Insulysin/IDE Antibody

IP, WBAF24962  
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Human Insulysin/IDE Antibody

CyTOF-ready, Flow, WBMAB2496 
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Recombinant Rat Insulysin/IDE Protein, CF

 6958-ZN 
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Human Insulysin/IDE Alexa Fluor® 488-conjugated Antibody

ICC/IFIC2496G 
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Human Insulysin/IDE Alexa Fluor® 700-conjugated Antibody

ICC/IFIC2496N 
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Human Insulysin/IDE Alexa Fluor® 647-conjugated Antibody

ICC/IFIC2496R 
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Human Insulysin/IDE Alexa Fluor® 750-conjugated Antibody

ICC/IFIC2496S 
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Human Insulysin/IDE Alexa Fluor® 594-conjugated Antibody

ICC/IFIC2496T 
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Human Insulysin/IDE Alexa Fluor® 350-conjugated Antibody

ICC/IFIC2496U 
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Human Insulysin/IDE Alexa Fluor® 405-conjugated Antibody

ICC/IFIC2496V 
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