Integrin alpha 2/CD49b: Products

Integrin alpha 2 is one of twelve Integrin alpha subunits that associates with the beta 1 subunit. Integrin alpha 2 beta 1 (VLA-2) is one of twelve integrin family adhesion receptors that share the beta 1 subunit. It is one of six very late antigens expressed on activated T cells. Divalent cations and intracellular (inside-out) signaling convert it to its most active, extended, and open conformation. a2b1 binds to Collagen types I, II, and III, Laminin, Decorin, E‑Cadherin, and Collectin molecules such as C1q. Platelet a2b1, also called GPIa, cooperates with GPVI to coordinate platelet collagen binding and activation. Adhesion is enhanced by crosstalk with Syndecan-1 or HGF R/c-Met and antagonized by crosstalk with Integrin alpha 1 beta 1. a2b1 is additionally expressed on select hematopoietic and non‑hematopoietic cells.

 

Showing 1-11 out of 11 Integrin alpha 2/CD49b Products

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Mouse Integrin  alpha 2/CD49b Antibody

CyTOF-ready, Flow, ICC/IF, WBAF1740 
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Mouse Integrin  alpha 2/CD49b Biotinylated Antibody

Flow, ICC/IF, WBBAF17401  
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Mouse Integrin alpha 2/CD49b Antibody

FlowMAB1740 
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Mouse Integrin alpha 2/CD49b (NP_032422) VersaClone cDNA

RDC1167 
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Mouse Integrin alpha 2/CD49b Alexa Fluor® 488-conjugated Antibody

FlowFAB1740G 
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Mouse Integrin alpha 2/CD49b Alexa Fluor® 700-conjugated Antibody

FlowFAB1740N 
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Mouse Integrin alpha 2/CD49b Alexa Fluor® 647-conjugated Antibody

FlowFAB1740R 
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Mouse Integrin alpha 2/CD49b Alexa Fluor® 750-conjugated Antibody

FlowFAB1740S 
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Mouse Integrin alpha 2/CD49b Alexa Fluor® 594-conjugated Antibody

FlowFAB1740T 
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Mouse Integrin alpha 2/CD49b Alexa Fluor® 350-conjugated Antibody

FlowFAB1740U 
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Mouse Integrin alpha 2/CD49b Alexa Fluor® 405-conjugated Antibody

FlowFAB1740V 
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