Integrin alpha 4 beta 1: Products

Integrins are transmembrane proteins that mediate interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM). Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metastatic and invasive potential of tumor cells. They exist as heterodimers consisting of alpha and beta subunits. Some alpha and beta subunits exhibit specificity for one another and may be designated as a VLA (very late antigen) member. Heterodimers often preferentially bind certain cell adhesion molecules, or constituents of the ECM. Although they have no catalytic activity, integrins can be part of multimolecular signaling complexes known as focal adhesions.

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Recombinant Human Integrin alpha 4 beta 1 Protein, CF

 5668-A42  
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BIO 1211


Selective α4β1 (VLA-4) inhibitor
39102  
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BIO 5192


Highly potent and selective inhibitor of integrin α4β1
50511  
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Recombinant Mouse Integrin alpha 4 beta 1 Protein, CF

 6054-A41  
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TCS 2314


α4β1 (VLA-4) antagonist
3900 
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LDV FITC


Fluorescent ligand for α4β1 (VLA-4)
4577 
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R-BC154


High affinity fluorescent α4β1/α9β1 inhibitor; mobilizes HSCs
6048 
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