Integrin alpha V beta 3: Products

Integrin alpha V beta 3 (aVb3) is a heterodimeric adhesion protein that is highly expressed on endothelial cells and osteoclasts. Active cell surface aVb3 binds to the extracellular matrix proteins Vitronectin, Fibronectin, Fibrinogen and Thrombospondin. It is essential for the maturation of osteoclasts and their bone resorption activity. Loss of aVb3 function during osteoclastogenesis causes osteoporosis. In addition, aVb3 enhances VEGF R2 mediated angiogenesis, IGF-1 mediated tumor cell invasiveness, and cell entry by several viruses.

Showing 1-8 out of 8 Integrin alpha V beta 3 Products

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Recombinant Human Integrin alpha V beta 3 Protein, CF

 3050-AV5  
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Human Integrin  alpha V beta 3 Antibody

B/N, Flow, IHC, IPMAB30504  
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Recombinant Mouse Integrin alpha V beta 3 Protein, CF

 7889-AV 
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Human Integrin  alpha V beta 3 PE-conjugated Antibody

FlowFAB3050P2  
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Human Integrin  alpha V beta 3 APC-conjugated Antibody

FlowFAB3050A 
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P11


Potent antagonist of alphavbeta3-vitronectin interaction; antiangiogenic
4744 
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Echistatin, α1 isoform


alphaVbeta3 and glycoprotein IIb/IIIa (integrin alphaIIbbeta3) inhibitor
32022  
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