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Jagged 1: Products

Mammalian Jagged proteins are homologs of the Drosophila Notch ligand, Serrate, and together with Delta-like proteins, constitute ligands for the mammalian Notch proteins. Jagged 1 and 2 are 180 kDa and 150 kDa type I transmembrane glycoproteins, respectively, that possess extracellular DSL (delta, serrate, lag-2 consensus sequence) domains necessary for binding to Notch receptors, along with 15-16 calcium-binding EGF-like repeats which modulate the binding affinity. Jagged-Notch signaling specifies cell fate, regulates pattern formation, defines boundaries between different cell types, and modulates cell proliferation and differentiation, especially during hematopoiesis, myogenesis, neurogenesis and development of the vasculature. Since both the ligands and receptors are transmembrane proteins, direct cell-cell interactions are thought to be required for functional Notch signaling.

Showing 1-26 out of 26 Jagged 1 Products

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Recombinant Human Jagged 1 Fc Chimera Protein, CF

 1277-JG11  
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Recombinant Rat Jagged 1 Fc Chimera Protein, CF

 599-JG11  
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Human Jagged 1 Antibody

B/N, IHC, WBAF12776  
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Rat Jagged 1 Antibody

B/N, CyTOF-ready, ELISA(Cap), Flow, WBAF5993  
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Human/Mouse/Rat Jagged 1 Antibody

CyTOF-ready, FlowMAB12775  
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Human/Mouse Jagged 1/Jagged 2 APC-conjugated Antibody

FlowFAB1726A1  
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Human/Mouse/Rat Jagged 1 APC-conjugated Antibody

FlowFAB1277A 
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Human/Mouse/Rat Jagged 1 Fluorescein-conjugated Antibody

FlowFAB1277F 
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Human Jagged 1 Antibody

B/NMAB127711  
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Human/Mouse Jagged 1/Jagged 2 PE-conjugated Antibody

FlowFAB1726P 
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Rat Jagged 1 Biotinylated Antibody

ELISA(Det), WBBAF599 
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Human Jagged 1 Biotinylated Antibody

WBBAF1277 
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Rat Jagged 1 Antibody

WBMAB599 
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Human/Mouse/Rat Jagged 1 Alexa Fluor® 488-conjugated Antibody

FlowFAB1277G 
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Human/Mouse/Rat Jagged 1 Alexa Fluor® 700-conjugated Antibody

FlowFAB1277N 
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Human/Mouse/Rat Jagged 1 Alexa Fluor® 647-conjugated Antibody

FlowFAB1277R 
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Human/Mouse/Rat Jagged 1 Alexa Fluor® 750-conjugated Antibody

FlowFAB1277S 
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Human/Mouse/Rat Jagged 1 Alexa Fluor® 594-conjugated Antibody

FlowFAB1277T 
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Human/Mouse/Rat Jagged 1 Alexa Fluor® 350-conjugated Antibody

FlowFAB1277U 
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Human/Mouse/Rat Jagged 1 Alexa Fluor® 405-conjugated Antibody

FlowFAB1277V 
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Human Jagged 1 Biotinylated Antibody

FlowBAM1277 
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Human Jagged 1 DuoSet ELISA

ELISADY1277-05 
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Rat Jagged 1 DuoSet ELISA

ELISADY599 
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Human Jagged 1 (NP_000205) VersaClone cDNA

RDC0722 
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Proteome Profiler Human sReceptor Array, Non-hematopoietic


Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
ARY01210  
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Proteome Profiler Rat XL Cytokine Array

ARY030 
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