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LAG-3: Products

LAG-3 (Lymphocyte activation gene-3; CD223) is a transmembrane protein that binds to MHC class II molecules and negatively regulates T cell receptor signaling. It is expressed on activated T cells, NK cells, and plasmacytoid dendritic cells (pDC). LAG-3 limits the expansion of activated T cells and pDC in response to select stimuli. Proteolytic shedding of LAG-3 enables normal T cell activation by removing the negative regulation. Binding of a homodimerized soluble LAG-3/Ig fusion protein to MHC class II molecules induces maturation of immature DC as well as secretion of pro-inflammatory cytokines by cytotoxic CD8+ T cells and NK cells.

Showing 1-25 out of 25 LAG-3 Products

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Recombinant Human LAG-3 Fc Chimera Protein, CF

 2319-L3 
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Human LAG-3 PE-conjugated Antibody

FlowFAB2319P5  
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Human LAG-3 Antibody

FlowMAB23193 
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Mouse LAG-3 Antibody

WBAF33281  
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Human LAG-3 PE-conjugated Antibody

FlowFAB23193P 
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Human LAG-3 Antibody

Flow, WBAF23192  
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Recombinant Mouse LAG-3 Fc Chimera Protein, CF

 3328-L3 
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Human LAG-3 Alexa Fluor® 700-conjugated Antibody

FlowFAB23193N1  
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Human LAG-3 Biotinylated Antibody

Flow, WBBAF23191  
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Human LAG-3 APC-conjugated Antibody

FlowFAB23193A 
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Human LAG-3 APC-conjugated Antibody

FlowFAB2319A 
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Human LAG-3 Fluorescein-conjugated Antibody

FlowFAB2319F 
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Mouse LAG-3 Antibody

FlowMAB33281 
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Human LAG-3 Antibody

WBMAB2319 
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Human LAG-3 PerCP-conjugated Antibody

FlowFAB2319C 
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Mouse LAG-3 Alexa Fluor® 700-conjugated Antibody

FlowFAB33281N 
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Human LAG-3 Alexa Fluor® 488-conjugated Antibody

FlowFAB23193G 
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Mouse LAG-3 PE-conjugated Antibody

FlowFAB33281P 
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Mouse LAG-3 PE-conjugated Antibody

FlowFAB3328P 
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Mouse LAG-3 Alexa Fluor® 488-conjugated Antibody

FlowFAB33281G 
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Mouse LAG-3 (NP_032505) VersaClone cDNA

RDC1539 
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Human LAG-3 DuoSet ELISA

ELISADY2319B 
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Cynomolgus Monkey LAG-3 (XP_005570011) VersaClone cDNA

RDC1696 
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Human LAG-3 (NP_002277) VersaClone cDNA

RDC1513 
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Proteome Profiler Human sReceptor Array, Hematopoietic


Contains 4 membranes - 2 spotted in duplicate with 48 different hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
ARY0111  
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