LAG-3: Products

LAG-3 (Lymphocyte activation gene-3; CD223) is a transmembrane protein that binds to MHC class II molecules and negatively regulates T cell receptor signaling. It is expressed on activated T cells, NK cells, and plasmacytoid dendritic cells (pDC). LAG-3 limits the expansion of activated T cells and pDC in response to select stimuli. Proteolytic shedding of LAG-3 enables normal T cell activation by removing the negative regulation. Binding of a homodimerized soluble LAG-3/Ig fusion protein to MHC class II molecules induces maturation of immature DC as well as secretion of pro-inflammatory cytokines by cytotoxic CD8+ T cells and NK cells.

Showing 1-28 out of 28 LAG-3 Products

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Human LAG-3 PE-conjugated Antibody

FlowFAB2319P7  
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Human LAG-3 Antibody

CyTOF-reported, Flow, WBMAB23193 
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Human LAG-3 Antibody

CyTOF-reported, Flow, WBAF23194  
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Mouse LAG-3 Antibody

WBAF33281  
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Human LAG-3 PE-conjugated Antibody

FlowFAB23193P 
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Human LAG-3 APC-conjugated Antibody

FlowFAB2319A2  
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Human LAG-3 Alexa Fluor® 700-conjugated Antibody

FlowFAB23193N1  
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Human LAG-3 Biotinylated Antibody

Flow, WBBAF23191  
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Human LAG-3 APC-conjugated Antibody

FlowFAB23193A 
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Human LAG-3 Antibody

WBMAB2319 
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Mouse LAG-3 Antibody

CyTOF-ready, FlowMAB33281 
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Human LAG-3 PerCP-conjugated Antibody

FlowFAB2319C 
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Human LAG-3 Fluorescein-conjugated Antibody

FlowFAB2319F 
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Human LAG-3 Alexa Fluor® 488-conjugated Antibody

FlowFAB23193G 
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Mouse LAG-3 Alexa Fluor® 700-conjugated Antibody

FlowFAB33281N 
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Mouse LAG-3 PE-conjugated Antibody

FlowFAB33281P 
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Mouse LAG-3 PE-conjugated Antibody

FlowFAB3328P 
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Mouse LAG-3 Alexa Fluor® 488-conjugated Antibody

FlowFAB33281G 
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Human LAG-3 Alexa Fluor® 647-conjugated Antibody

FlowFAB23193R 
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Human LAG-3 Alexa Fluor® 750-conjugated Antibody

FlowFAB23193S 
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Human LAG-3 Alexa Fluor® 594-conjugated Antibody

FlowFAB23193T 
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Human LAG-3 Alexa Fluor® 350-conjugated Antibody

FlowFAB23193U 
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Human LAG-3 Alexa Fluor® 405-conjugated Antibody

FlowFAB23193V 
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Mouse LAG-3 Alexa Fluor® 647-conjugated Antibody

FlowFAB33281R 
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Mouse LAG-3 Alexa Fluor® 750-conjugated Antibody

FlowFAB33281S 
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Mouse LAG-3 Alexa Fluor® 594-conjugated Antibody

FlowFAB33281T 
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Mouse LAG-3 Alexa Fluor® 350-conjugated Antibody

FlowFAB33281U 
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Mouse LAG-3 Alexa Fluor® 405-conjugated Antibody

FlowFAB33281V 
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