LAMP-2/CD107b: Products

Lysosomal associated membrane protein 2 (LAMP-2), also known as CD107b and LGP110, is an approximately 110 kDa transmembrane glycoprotein that is a major component of lysosomal membranes. Within the lumenal domain, human LAMP2 shares approximately 64% aa sequence identity with mouse and rat LAMP-2. LAMP-2 itself is subject to lysosomal degradation following cleavage of its lumenal domain. It mediates the lysosomal uptake of the chaperone HSC73 in complex with cargo proteins and is required for the lysosomal destruction of autophagic vacuoles. In cytotoxic T cells and mast cells, LAMP-2 is expressed in the membranes of intracellular granules that contain effector molecules such as perforin, granzymes, eicosanoids, and histamine. Up-regulated LAMP-2 at the plasma membrane serves as an indicator of cell activation of CD8+ T cells, mast cells, monocytes, and platelets. LAMP-2 is a native ligand for lectins Galectin-1 and Galectin-3.

Showing 1-15 out of 15 LAMP-2/CD107b Products

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Human LAMP2/CD107b Antibody

CyTOF-ready, Flow, ICC/IF, WBAF6228 
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Human LAMP2/CD107b Antibody

CyTOF-ready, Flow, ICC/IF, WBMAB6228 
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Human LAMP-2/CD107b Alexa Fluor® 488-conjugated Antibody

Flow, ICC/IFIC6228G 
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Human LAMP2/CD107b Biotinylated Antibody

ICC/IFBAM6228 
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Human LAMP-2/CD107b PE-conjugated Antibody

FlowIC6228P 
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Human LAMP-2/CD107b APC-conjugated Antibody

FlowIC6228A 
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Recombinant Human LAMP-2/CD107b Protein, CF

 6228-LM 
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Human LAMP-2A/CD107b (NP_002285) VersaClone cDNA

RDC0977 
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Human LAMP-2B/CD107b (NP_054701) VersaClone cDNA

RDC1003 
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Human LAMP-2/CD107b Alexa Fluor® 700-conjugated Antibody

FlowIC6228N 
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Human LAMP-2/CD107b Alexa Fluor® 647-conjugated Antibody

FlowIC6228R 
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Human LAMP-2/CD107b Alexa Fluor® 750-conjugated Antibody

FlowIC6228S 
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Human LAMP-2/CD107b Alexa Fluor® 594-conjugated Antibody

FlowIC6228T 
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Human LAMP-2/CD107b Alexa Fluor® 350-conjugated Antibody

FlowIC6228U 
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Human LAMP-2/CD107b Alexa Fluor® 405-conjugated Antibody

FlowIC6228V 
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