LRH-1/NR5A2: Products

Liver receptor homolog-1 (LRH-1, FTF, CPF, hB1F, FTZ-F1b; NR5A2) is a member of the orphan nuclear receptor family. LRH-1 is a mammalian homolog of the Drosophila fushi tarazu Factor 1 gene product. LRH-1 is thought to be critical for development because LRH-1 knockout mice are not viable. LRH-1 is expressed in the liver, intestine, pancrease, ovary and preadipocytes.

LRH-1 is involved in the regulation of genes which participate in steroid, bile acid and cholesterol homeostasis. A role for LRH-1 in steroidogenesis is supported by its expression in ovarian granulosa cells and corpus luteum. LRH-1 has been shown to regulate transcription of several steroidogenic genes and is known to modulate the expression of aromatase in breast adipose tissue.

Showing 1-4 out of 4 LRH-1/NR5A2 Products

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Human LRH-1/NR5A2 MAb (Clone H2325)

ELISA, IP, WBPP-H2325-005  
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Human LRH-1/NR5A2 MAb (Clone K8801)

IP, WBPP-K8801-00 
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DLPC


LRH-1 agonist; regulates bile acid metabolism
43781
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ML 179


Selective liver receptor homolog 1 (LRH1) inverse agonist
4957
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