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Leptin/OB: Products

Leptin, also known as OB, is a polypeptide hormone that regulates adipose tissue mass and energy balance. In mice (ob/ob) and humans, inactivating mutations of the OB gene can cause obesity. Leptin signals through the transmembrane Leptin R in the hypothalamus but can also bind shorter and soluble forms of Leptin R which do not signal. Adipocytes increase Leptin expression as cell size increases, resulting in depressed appetite and increased energy expenditure. Low Leptin levels prompt increased appetite and decreased energy expenditure. Leptin can also block the onset of puberty or menses during starvation, extreme exercise-induced weight loss, anorexia, or cancer-induced cachexia.

Showing 1-8 out of 8 Leptin/OB Products

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Contains 4 membranes - each spotted in duplicate with 55 different cytokine antibodies
ARY00741  
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Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
ARY022B1  
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Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
ARY028 
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Contains 4 membranes - each spotted in duplicate with 53 different cytokine antibodies
ARY01512  
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Contains 4 membranes - each spotted in duplicate with 38 different obesity-related antibodies
ARY0134  
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Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies
ARY026 
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Contains 4 membranes-each spotted in duplicate with 58 different obesity-related antibodies
ARY024 
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Contains 4 membranes - each spotted in duplicate with 30 different obesity-related antibodies
ARY016 
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