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MBL: Products

Mannose/mannan-binding lectin (MBL) is a secreted glycoprotein in the collectin family of pattern-recognition molecules. It contains a cysteine-rich region, a collagen-like segment, and a C-type lectin domain that binds to neutral bacterial carbohydrates. The collagen-like region mediates MBL association into disulfide-stabilized trimers which further associate into complexes containing three or four copies of the basic trimer. MBL is secreted by hepatocytes and opsonizes bacteria through interactions with microbial carbohydrates. MBL multimers can associate with the serine proteases MASP-1, -2, and -3 and promote their cleavage of Complement Component C3. Proteolytic cleavage of C3 triggers activation of the complement system and formation of the membrane attack complex, leading to destruction of opsonized bacteria. Opsonized apoptotic material is cleared by the scavenger receptor CD91.

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Human Magnetic Luminex Assay

LXSAHM7  
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Build your own with our Luminex Assay Customization Tool.

Human Luminex Assay

LXSAH4  
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Build your own with our Luminex Assay Customization Tool.

Human MBL Antibody

ELISA(Cap), WBAF23075  
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Human MBL Quantikine ELISA Kit

ELISADMBL002  
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Human MBL Biotinylated Antibody

ELISA(Det), WBBAF23071  
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Recombinant Human MBL Protein, CF

 9086-MB 
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Human MBL Antibody

B/NMAB230711  
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Human MBL Antibody

WBMAB2307 
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Human MBL DuoSet ELISA

ELISADY2307 
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Quantikine Immunoassay Control Set 839 for Human MBL


For use with catalog number DMBL00
CtrlQC118 
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