MET Inhibitors: Products

HGF receptor, a product of the proto-oncogene c-met, is a heterodimeric transmembrane glycoprotein that is a receptor-type tyrosine kinase. c-MET is synthesized as a single-chain precursor (pr170) which undergoes post-translational glycosylation and proteolytic cleavage to give rise to the heterodimeric mature form.

Showing 1-9 out of 9 MET Inhibitors Products

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SU 5416


VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
30374  
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K 252a


Protein kinase inhibitor
16835  
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PF 04217903 mesylate


Highly selective MET inhibitor
42391  
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Crizotinib


Potent c-MET/ALK inhibitor
43682  
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SU 11274


Selective inhibitor of MET kinase activity
41015  
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PHA 665752


Potent and selective MET inhibitor
269322  
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SGX 523


Selective and potent c-MET kinase inhibitor
5356 
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Norleual


Highly potent HGF/c-MET inhibitor; also AT4 antagonist
5369 
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XL 184


Potent VEGFR inhibitor; also inhibits other RTKs
5422 
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