Mineralocorticoid R/NR3C2: Products

Mineralocorticoid Receptor (MR) is a member of the nuclear hormone receptor family. Upon binding of ligand (aldosterone or corticosterone) mineralocorticoid receptors translocate to the nucleus and can form either homo or heterodimers. MR dimers bind to the mineralocorticoid response element (AGAACANNNTGTTCT) to regulate gene transcription. There are four known isoforms of MR.

Mineralocorticoid Receptos are expressed in the kidney, gut, brain, pituitary, hypothalamus and heart. MR plays a critical role in regulating electrolyte and fluid balance in the kidney, as well as having specific roles in the central nervous system. The protein is expressed as a 107 kDa nuclear form. MR and glucocorticoid receptors (GR) can cooperatively form heterodimers.

Showing 1-7 out of 7 Mineralocorticoid R/NR3C2 Products

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Human Mineralocorticoid R/NR3C2 Antibody

IHC, WBMAB4369 
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Human Mineralocorticoid R/NR3C2 Antibody

ELISA, IHC, IP, WBPP-H3122-00 
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RU 28318, potassium salt


Potent, selective mineralocorticoid receptor antagonist
16726  
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Spironolactone


Mineralocorticoid receptor antagonist
29681  
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Eplerenone


Selective mineralocorticoid receptor antagonist
23971  
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RU 26752


Mineralocorticoid receptor antagonist
2970 
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Canrenone


Mineralocorticoid receptor antagonist
3281 
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