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Myeloperoxidase/MPO: Products

Myeloperoxidase (MPO) is a heme-containing enzyme belonging to the XPO subfamily of peroxidases. It is an abundant neutrophil and monocyte glycoprotein that catalyzes the hydrogen peroxide dependent formation of hypochlorus acid (HOCl) and other reactive species. Enzymatically active MPO is a disulfide-linked tetramer that contains two heme groups and two copies each of the heavy and light chains. MPO binds Albumin, MMR, Cytokeratin 1 on vascular endothelial cells, HMW Kininogen, and Integrin CD11b/CD18 on neutrophils. These interactions promote MPO clearance, a reduction of nitric oxide and bradykinin levels, reduced vasodilation, and continued neutrophil activation. Neutrophil MPO is stored in cytoplasmic azurophilic granules. Upon cellular activation and degranulation, MPO is delivered into phagosomes where it is required for the killing of phagocytosed bacteria. Activated neutrophils also release granule contents extracellularly. Elevated plasma MPO levels have been associated with a variety of clinical conditions including systemic inflammation, eclampsia, risk of cardiovascular events, vascular endothelial dysfunction, severity of multiple sclerosis, and prospective mortality and oxidative stress during hemodialysis.

Showing 1-19 out of 19 Myeloperoxidase/MPO Products

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Human Magnetic Luminex Assay

LXSAHM7  
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Human Myeloperoxidase Quantikine ELISA Kit

ELISADMYE00B6  
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Human Luminex Assay

LXSAH4  
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Human/Mouse Myeloperoxidase/MPO Antibody

ICC/IF, IHC, SW, WBAF36675  
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Human/Mouse Myeloperoxidase/MPO Antibody

ICC/IF, IHC, WBMAB31742  
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Recombinant Human Myeloperoxidase Protein, CF

 3174-MP1  
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Mouse Myeloperoxidase DuoSet ELISA

ELISADY36674  
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Human Myeloperoxidase/MPO Biotinylated Antibody

WBBAF31741  
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Recombinant Mouse Myeloperoxidase Protein, CF

 3667-MP 
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Human Myeloperoxidase/MPO Antibody

ICC/IF, SW, WBAF3174 
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Human Myeloperoxidase DuoSet ELISA

ELISADY31742  
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Proteome Profiler Human XL Cytokine Array Kit


Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
ARY022B5  
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Mouse Myeloperoxidase/MPO Biotinylated Antibody

WBBAF3667 
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Quantikine Immunoassay Control Set 915 Human Myeloperoxidase


For use with catalog number DMYE00B
CtrlQC211 
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Human Myeloperoxidase Luminex Performance Assay

LUCB31741  
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Proteome Profiler Mouse XL Cytokine Array


Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
ARY028 
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PF 06281355


Selective myeloperoxidase (MPO) inhibitor
6004 
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Proteome Profiler Human Adipokine Array Kit


Contains 4 membranes-each spotted in duplicate with 58 different obesity-related antibodies
ARY024 
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Proteome Profiler Human sReceptor Array, Hematopoietic


Contains 4 membranes - 2 spotted in duplicate with 48 different hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
ARY0111  
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