NPR-1: Products

Natriuretic peptide receptor A/guanylate cyclase A (NPR-1), also called NPRA or GC-A, is a 120 - 140 kDa type I transmembrane glycoprotein that is the primary receptor for natrietic peptides ANP and BNP. Binding of ANP to the extracellular ligand binding domain (aa 54 - 415), plus ATP to the intracellular kinase homology domain (aa 528 - 805) activates a cytoplasmic guanylate cyclase (aa 840 - 1023). NPR-1 is expressed most highly in kidney, adrenal and adipose tissue. Human NPR-1 extracellular domain shows 86%, 44% and 34% aa identity with mouse NPR-1, human NPRB and human NPRC, respectively.

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Human NPR-1 Antibody

WBMAB4860 
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Mouse NPR-1 Antibody

IHCMAB3974 
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Mouse NPR-1 Antibody

WBAF3974 
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