Nectin-1: Products

Nectins are type I transmembrane glycoproteins that are calcium-independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs). Homology has led to their designation as poliovirus receptor-related (PRR) proteins, but nectins do not bind poliovirus. The extracellular domains of the nectin family form cis-homodimers (same cell), followed by homophilic or heterophilic trans-dimers (across cells) that organize intercellular junctions. Nectin-1, also known as CD111, PRR1 and herpes virus entry mediator C (HVEC) has a secreted splice variant. Nectin-1, Nectin-2 (CD112, PRR2, HVEB) and Nectin-3 (PRR3) are concentrated in adherens junctions and exist on neurons, endothelial cells, epithelial cells and fibroblasts. Nectin-4 is mainly expressed in the placenta; a soluble form is generated via the action of TACE/ADAM17.

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Recombinant Human Nectin-1 Protein, CF

 2880-N1 
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Human/Mouse Nectin-1 Antibody

WBAF2880 
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Human Nectin-1 APC-conjugated Antibody

FlowFAB2880A 
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Human Nectin-1 Antibody

FlowMAB2880 
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Human Nectin-1 Biotinylated Antibody

WBBAF2880 
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Human Nectin-1 (NP_002846) VersaClone cDNA

RDC1574 
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