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Neprilysin/CD10: Products

The neprilysin (NEP) family of zinc metallopeptidases includes neprilysin, endothelin-converting enzyme-2 (ECE-2), PEX, damage induced neuronal endopeptidase (DINE), Kell and several neprilysin-like proteins. Neprilysin is expressed at the cell surface of a variety of cell types. Enzymatically, neprilysin functions both as an endopeptidase with a thermolysin-like specificity and as a dipeptidylcarboxypeptidase. Neprilysin has been shown to be involved in the degradation of enkephalins in the mammalian brain and the inactivation of circulating atrial natriuretic peptide. Neprilysin has also been identified as the common acute lymphoblastic leukemia antigen (CALLA), and to be expressed on the surface of lymphocytes in some disease states. These and other observations have resulted in considerable clinical interest in neprilysin as a potential target for analgesics and antihypertensive drugs. Neprilysin is also a major degrading enzyme of amyloid-beta peptide (A-beta) in the brain, indicating that down-regulation of neprilysin activity, which could be caused by aging, can contribute to the development of Alzheimers disease by promoting A-beta accumulation.

Showing 1-24 out of 24 Neprilysin/CD10 Products

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Mouse Neprilysin/CD10 Antibody

B/N, ELISA(Cap), IHC, IP, WBAF11262  
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Human Neprilysin/CD10 Antibody

CyTOF-ready, ELISA(Cap), Flow, IHC, IP, WBAF11822  
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Recombinant Human Neprilysin (CHO-expressed) Protein, CF

 1182-ZNC2  
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Human/Mouse Neprilysin/CD10 Antibody

IHC, WBMAB11261  
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Human Neprilysin/CD10 Biotinylated Antibody

ELISA(Det), Flow, IHC, WBBAF1182 
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Human Neprilysin DuoSet ELISA

ELISADY11823  
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Human Neprilysin/CD10 Antibody

CyTOF-ready, Flow, WBMAB1182 
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Human Neprilysin/CD10 Antibody

WBMAB118211  
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Mouse Neprilysin/CD10 Biotinylated Antibody

ELISA(Det), WBBAF1126 
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Human Neprilysin/CD10 PE-conjugated Antibody

FlowFAB8160P 
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Mouse Neprilysin DuoSet ELISA

ELISADY11261  
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Sacubitril calcium


Membrane metallo-endopeptidase (neprilysin) inhibitor prodrug; orally bioavailable
5772 
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Recombinant Mouse Neprilysin (CHO-expressed) Protein, CF

 1126-ZNC 
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Human Neprilysin/CD10 Alexa Fluor® 488-conjugated Antibody

FlowFAB1182G 
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Human Neprilysin/CD10 Alexa Fluor® 700-conjugated Antibody

FlowFAB1182N 
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Human Neprilysin/CD10 Alexa Fluor® 647-conjugated Antibody

FlowFAB1182R 
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Human Neprilysin/CD10 Alexa Fluor® 750-conjugated Antibody

FlowFAB1182S 
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Human Neprilysin/CD10 Alexa Fluor® 594-conjugated Antibody

FlowFAB1182T 
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Human Neprilysin/CD10 Alexa Fluor® 350-conjugated Antibody

FlowFAB1182U 
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Human Neprilysin/CD10 Alexa Fluor® 405-conjugated Antibody

FlowFAB1182V 
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Proteome Profiler Human Protease Array Kit


Contains 4 membranes - each spotted in duplicate with 35 different protease antibodies
ARY021B5  
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Proteome Profiler Human Protease/Protease Inhibitor Array


Contains 4 membranes-2 spotted in duplicate with antibodies against 35 different proteases and 2 spotted in duplicate with antibodies against 32 different protease inhibitors
ARY0251  
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Proteome Profiler Human Kidney Biomarker Array Kit


Contains 4 membranes - each spotted in duplicate with 38 different kidney biomarker antibodies
ARY019 
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Proteome Profiler Rat XL Cytokine Array


Contains 4 membranes-each spotted in duplicate with 79 different cytokine antibodies
ARY030 
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