Nicotinic Acetylcholine R alpha 7/CHRNA7: Products

The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. nAChR alpha 7/CHRNA7 forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once nAChR alpha 7/CHRNA7 binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Showing 1-27 out of 27 Nicotinic Acetylcholine R alpha 7/CHRNA7 Products

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α-Bungarotoxin


alpha7 subtype-selective nAChR antagonist
213318  
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Methyllycaconitine citrate


alpha7 neuronal nicotinic receptor antagonist
102920  
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AR-R 17779 hydrochloride


alpha7-selective agonist
3964 
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PNU 120596


Positive allosteric modulator of alpha7 nAChR; active in vivo
24988  
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PHA 543613 hydrochloride


Potent and selective alpha7 nAChR agonist
30922  
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PNU 282987


Selective alpha7 nAChR agonist
23032  
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Ivermectin


Allosteric modulator of alpha7 nicotinic receptors
12602  
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PHA 568487


alpha7-selective agonist
31341  
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Tropisetron hydrochloride


Potent 5-HT3 receptor antagonist; also partial agonist of alpha7 nAChR
24594  
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MG 624


alpha7 neuronal nicotinic receptor antagonist
13561  
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3-Bromocytisine


Potent agonist of alpha4beta4, alpha4beta2 and alpha7 nACh receptors
35491  
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S 24795


Partial agonist at alpha7 nAChR
3518 
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Ivermectin B1a-d2


Deuterated ivermectin B1a (Cat. No. 1260)
5156 
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NS 1738


Positive allosteric modulator of alpha7 nAChR; active in vivo
29952  
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LY 2087101


Potentiator of alpha7 nAChRs
4141 
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DMAB-anabaseine dihydrochloride


Partial agonist at alpha7 nAChR; also alpha4beta2 antagonist
2241 
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CCMI


Positive allosteric modulator of alpha7 nAChR
3837 
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A 844606


Selective alpha7 nAChR partial agonist
4477 
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TQS


Positive allosteric modulator of alpha7 nAChRs
4233 
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4BP-TQS


Allosteric agonist at alpha7 nAChR
42341  
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SEN 12333


alpha7 nAChR agonist; histamine H3 antagonist
4441 
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GTS 21 dihydrochloride


Partial agonist at alpha7 nAChR. Not for Sale in the USA
4557 
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TC 1698 dihydrochloride


alpha7-selective agonist
2518 
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A 582941


Partial agonist at alpha7 nAChR
4341 
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A 867744


Positive allosteric modulator of alpha7 nAChR
4571 
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α-Conotoxin ImI


alpha7 and alpha9 selective nAChR antagonist
3119 
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Human nAChR alpha 7/CHRNA7 (NP_000737) VersaClone cDNA

RDC0282 
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