Nicotinic Acetylcholine R alpha 7/CHRNA7: Products

The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. nAChR alpha 7/CHRNA7 forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once nAChR alpha 7/CHRNA7 binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Showing 1-29 out of 29 Nicotinic Acetylcholine R alpha 7/CHRNA7 Products

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Methyllycaconitine citrate


α7 neuronal nicotinic receptor antagonist
102925
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α-Bungarotoxin


α7 subtype-selective nAChR antagonist
213321
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Ivermectin


Allosteric modulator of α7 nicotinic receptors
12603
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PNU 282987


Selective α7 nAChR agonist
23033
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PNU 120596


Positive allosteric modulator of α7 nAChR; active in vivo
249811
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Tropisetron hydrochloride


Potent 5-HT3 receptor antagonist; also partial agonist of α7 nAChR
24594
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NS 1738


Positive allosteric modulator of α7 nAChR; active in vivo
29952
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AR-R 17779 hydrochloride


α7-selective agonist
3964
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MG 624


α7 neuronal nicotinic receptor antagonist
13562
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DMAB-anabaseine dihydrochloride


Partial agonist at α7 nAChR; also α4β2 antagonist
2241
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TC 1698 dihydrochloride


α7-selective agonist
2518
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PHA 543613 hydrochloride


Potent and selective α7 nAChR agonist
30924
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PHA 568487


α7-selective agonist
31342
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S 24795


Partial agonist at α7 nAChR
3518
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3-Bromocytisine


Potent agonist of α4β4, α4β2 and α7 nACh receptors
35491
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CCMI


Positive allosteric modulator of α7 nAChR
3837
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LY 2087101


Potentiator of α7 nAChRs
4141
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TQS


Positive allosteric modulator of α7 nAChRs
42331
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4BP-TQS


Allosteric agonist at α7 nAChR
42341
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A 582941


Partial agonist at α7 nAChR
4341
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SEN 12333


α7 nAChR agonist; histamine H3 antagonist
4441
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A 844606


Selective α7 nAChR partial agonist
4477
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GTS 21 dihydrochloride


Partial agonist at α7 nAChR. Not for Sale in the USA
4557
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A 867744


Positive allosteric modulator of α7 nAChR
4571
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Ivermectin B1a-d2


Deuterated ivermectin B1a (Cat. No. 1260)
5156
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α-Conotoxin ImI


α7 and α9 selective nAChR antagonist
3119
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NS 6740


High affinity α7 nAChR partial agonist; anti-inflammatory. Not for Sale in the USA
6139
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NS 6784 hydrochloride


α7 nAChR agonist. Not for Sale in the USA
6140
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Human nAChR alpha 7/CHRNA7 (NP_000737) VersaClone cDNA

RDC0282 
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