OX40/TNFRSF4: Products

OX40 (CD134; TNFRSF4) is a T cell costimulatory molecule of the TNF receptor superfamily that coordinates with other costimulators (CD28, CD40, CD30, CD27 and 4-1BB) to manage the activation of the immune response. OX40 is upregulated on antigen activated CD4+ and CD8+ T cells with costimulation by CD40-CD40 Ligand and CD28-B7. OX40 interactions with OX40 Ligand on antigen presenting cells enhances T cell survival, proliferation, and cytokine production. It also inhibits the conversion of effector T cells into regulatory T cells (Tregs) and can promote the maintenance of and recall response in memory T cells. OX40 is constitutively expressed on Tregs where it promotes Treg proliferation and immunosuppressive activity. OX40-OX40 Ligand signaling is involved in allergic airway inflammation, graft-versus-host disease, and autoimmune disease.

Showing 1-15 out of 15 OX40/TNFRSF4 Products

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Recombinant Human OX40/TNFRSF4 Fc Chimera Protein, CF

 3388-OX1  
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Recombinant Mouse OX40/TNFRSF4 Fc Chimera Protein, CF

 1256-OX1  
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Human OX40/TNFRSF4 Antibody

Flow, WBAF3388 
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Human OX40/TNFRSF4 Antibody

Flow, WBMAB3388 
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Human OX40/TNFRSF4 Biotinylated Antibody

Flow, WBBAF3388 
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Mouse OX40/TNFRSF4 Antibody

Func, WBAF12561  
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Mouse OX40/TNFRSF4 PE-conjugated Antibody

FlowFAB1256P 
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Human OX40/TNFRSF4 Fluorescein-conjugated Antibody

FlowFAB3388F 
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Human OX40/TNFRSF4 PE-conjugated Antibody

FlowFAB3388P 
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Human OX40/TNFRSF4 APC-conjugated Antibody

FlowFAB3388A 
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Mouse OX40/TNFRSF4 Biotinylated Antibody

WBBAF1256 
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Mouse OX40/TNFRSF4 (NP_035789) VersaClone cDNA

RDC0987 
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Human OX40/TNFRSF4 (NP_003318) VersaClone cDNA

RDC0360 
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Recombinant Rat OX40/TNFRSF4 Fc Chimera Protein, CF

 8584-OX 
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Rat OX40/TNFRSF4 (NP_037181) VersaClone cDNA

RDC0361 
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