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Osteoprotegerin/TNFRSF11B: Products

Osteoprotegerin (OPG)/osteoclastogenesis inhibitory factor (OCIF) is a member of the TNF receptor superfamily and is now referred to as TNFRSF11B. It is an osteoblast secreted decoy receptor that binds specifically to osteoprotegrin ligand (OPGL/TNFSF11) to inhibit osteoblast maturation. It is also a decoy receptor for TRAIL and inhibits TRAIL-induced apoptosis. Human and mouse OPG share approximately 84% and 94% amino acid sequence identity, respectively, with rat OPG. Natural OPG exists predominantly as disulfide-linked dimers.

Showing 1-3 out of 3 Osteoprotegerin/TNFRSF11B Products

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DY80530  
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MOP0022  
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DY4595  
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