Osteoprotegerin/TNFRSF11B: Products

Osteoprotegerin (OPG), also known as OCIF and TNFRSF11B, is a secreted TNF superfamily receptor that regulates bone density. OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells, fibroblasts, and endothelial cells. OPG functions as a decoy receptor for TRANCE/RANK L and TRAIL. OPG regulates the cell surface expression of TRANCE and its ability to stimulate osteoclastogenesis. Dysregulation of OPG/TRANCE interactions can lead to juvenile Paget’s disease, osteoporosis, bone loss, and vascular calcification.

Showing 1-8 out of 8 Osteoprotegerin/TNFRSF11B Products

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ELISA(Det), ICC/IF, IHC, WBBAF8053  
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B/N, IHC, WBAF8053  
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ELISA(Det), IHC, WBBAF4595  
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B/N, IHC, WBAF4594  
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B/NMAB8054  
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MAB80514  
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ELISA(Cap), WBMAB45913  
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WBMAB4592  
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