Osteoprotegerin/TNFRSF11B: Products

Osteoprotegerin (OPG), also known as OCIF and TNFRSF11B, is a secreted TNF superfamily receptor that regulates bone density. OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells, fibroblasts, and endothelial cells. OPG functions as a decoy receptor for TRANCE/RANK L and TRAIL. OPG regulates the cell surface expression of TRANCE and its ability to stimulate osteoclastogenesis. Dysregulation of OPG/TRANCE interactions can lead to juvenile Paget’s disease, osteoporosis, bone loss, and vascular calcification.

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Recombinant Human Osteoprotegerin/TNFRSF11B Protein

 6945-OS 
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Recombinant Human Osteoprotegerin/TNFRSF11B Protein, CF

 6945-OS/CF 
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Recombinant Mouse Osteoprotegerin/TNFRSF11B Fc Chimera, CF

 459-MO13  
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Recombinant Human Osteoprotegerin/TNFRSF11B Protein


A New and Improved rhOPG is Now Available! The new protein has ~2 fold better activity!
New Product 6945-OS
 185-OS9  
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Recombinant Human Osteoprotegerin/TNFRSF11B Protein, CF


A New and Improved rhOPG is Now Available! The new protein has ~2 fold better activity!
New Product 6945-OS/CF
 185-OS/CF9  
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