P2X1/P2RX1: Products

Biologic responses to ATP, ADP, and other extracellular nucleotides are mediated by P2-nucleotide receptors belonging to 2 major classes: G protein-coupled P2Y receptors and nucleotide-gated ion channel P2X receptors. P2RX1 functions as a ligand-gated ion channel with relatively high calcium permeability. Mouse studies suggest that this receptor is essential for normal male reproductive function. The development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.

Showing 1-9 out of 9 P2X1/P2RX1 Products

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BzATP triethylammonium salt


Photoaffinity label for ATPase; also P2X7 agonist and P2X1/P2Y1 partial agonist
33125  
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NF 449


Highly selective P2X1 antagonist
139112  
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NF 279


Potent and selective P2X1 antagonist
11998  
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NF 023


Selective, competitive P2X1 antagonist
12405  
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MRS 2219


Potentiates P2X1-mediated responses
1203 
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NF 157


Selective P2Y11/P2X1 antagonist
24506  
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Ro 0437626


Selective P2X1 antagonist
2188 
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PPNDS


Potent, selective P2X1 antagonist
13091  
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Human P2X1/P2RX1 (NP_002549) VersaClone cDNA

RDC0513 
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