PAK: Products

PAK (p21-activated kinases) are a family of serine/threonine kinases within the STE ser/thr protein kinase superfamily that play roles in various oncogenic signaling pathways. Cytoskeletal remodeling, motility, proliferation, and aberrant response to apoptosis and mitosis signals are among oncogenic cell functions coordinated by PAK family members. Group I (PAK1, PAK2 and PAK3, also called alpha, gamma and beta, respectively) contain auto-inhibitory and SH3 domains, in addition to the p21-binding and kinase domains present in Group II (PAK4, PAK6 and PAK7).

Showing 1-7 out of 7 PAK Products

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IPA 3


Group I PAK inhibitor
362218
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Phospho-PAK (T402) Antibody

WBPPS058 
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FRAX 486


Potent PAK inhibitor; brain penetrant and orally bioavailable
51901
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PIR 3.5


Negative control of IPA 3 (Cat. No. 3622)
42122
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FRAX 597


Potent group I PAK inhibitor
6029
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G 5555


High affinity group 1 PAK inhibitor
6051
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NVS PAK1 C


Negative control of NVS PAK1 1 (Cat. No. 6132)
6133
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