PAR2: Products

Protease-Activated Receptor 2 (PAR2) is a protease activated 7-transmembrane G-protein-coupled receptor. Human PAR2 contains a cleavage site for trypsin, mast cell tryptase or coagulation factor VIIa or Xa, 11 amino acids (aa) C-terminal to the signal sequence. Cleavage creates a tethered ligand that activates the 361 aa receptor. PAR2 is expressed in kidney, pancreas, stomach, intestine, airway, skin, bladder and brain; activation stimulates release of inflammatory and nociceptive mediators. PAR2 is downregulated by ubiquination, endocytosis and degradation. Mature human PAR2 shows 78% amino acid identity with mouse PAR2 over the extracellular portions.

Showing 1-13 out of 13 PAR2 Products

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SLIGKV-NH2


PAR2 receptor agonist
30101  
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SLIGRL-NH2


PAR2-activating peptide
14685  
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FSLLRY-NH2


PAR2 peptide antagonist
47514  
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Human PAR2 Antibody

FlowMAB3949 
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2-Furoyl-LIGRLO-amide


Potent and selective PAR2 agonist
30152  
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Human PAR2 PE-conjugated Antibody

FlowFAB3949P2  
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LRGILS-NH2


Control peptide for SLIGRL-NH2 (Cat. No. 1468)
3394 
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Human PAR2 APC-conjugated Antibody

FlowFAB3949A 
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AC 55541


Potent and selective PAR2 agonist
33694  
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AC 264613


PAR2 receptor agonist
3370 
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VKGILS-NH2


Control peptide for SLIGKV-NH2 (Cat. No. 3010)
3392 
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Mouse PAR2 (NP_032000) VersaClone cDNA

RDC0167 
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Human PAR2 (NP_005233) VersaClone cDNA

RDC0166 
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