PDGF R alpha: Products

PDGF isoforms exert their cellular effects by binding to the structurally similar receptor tyrosine kinases (RTK), PDGF R alpha (CD140a) and PDGF R beta (CD140b). PDGF-AA, PDGF-BB, PDGF-CC, PDGF-DD and PDGF-AB isofoms bind the two distinct cell surface PDGF receptors with different affinities. Both PDGF R alpha and PDGF R beta are members of the class III subfamily of RTK which are characterized by the presence of five immunoglobulin-like domains in their extracellular region and a split kinase domain in their intracellular region. PDGF binding induces receptor homo- and heterodimerization leading to signal transduction. The expression of PDGF alpha and beta receptors is independently regulated in various cell types.

Showing 1-16 out of 16 PDGF R alpha Products

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B/N, IHC, WBAF106211  
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B/N, IHC, WBAF-307-NA9  
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B/N, IHC, WBMAB3229  
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FlowFAB1264A1  
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Flow, IPMAB12646  
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FlowFAB1264P2  
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IHC, WBAF21141  
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IHC, WBBAF10621  
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IHC, WBAF21141 
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WBBAF3222  
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WBMAB10621  
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FlowFAB1062P 
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FlowFAB1264F 
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FlowFAB1264N 
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FlowFAB1062G 
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FlowFAB1062A 
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