PDGF R beta: Products

PDGF isoforms exert their cellular effects by binding to the structurally similar receptor tyrosine kinases (RTK), PDGF R alpha (CD140a) and PDGF R beta (CD140b). PDGF-AA, PDGF-BB, PDGF-CC, PDGF-DD and PDGF-AB isofoms bind the two distinct cell surface PDGF receptors with different affinities. Both PDGF R alpha and PDGF R beta are members of the class III subfamily of RTK which are characterized by the presence of five immunoglobulin-like domains in their extracellular region and a split kinase domain in their intracellular region. PDGF binding induces receptor homo- and heterodimerization leading to signal transduction. The expression of PDGF alpha and beta receptors is independently regulated in various cell types.

Showing 1-15 out of 15 PDGF R beta Products

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B/N, Flow, IHC, WBAF38511  
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IHC, WBAF10425  
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Flow, IHC, IP, WBMAB12639  
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FlowFAB1263P3  
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IHC, WBBAF10421  
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ICC/IF, SW, WBMAB9027 
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SW, WBAF17671  
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WBAF2316 
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Flow, WBBAF3851  
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FlowFAB1263F2  
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WBMAB10421  
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WBMAB3851  
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FlowFAB1263N 
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FlowFAB1263C 
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FlowFAB1263A 
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