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PDGF-DD: Products

Platelet-derived growth factor-D (PDGF-D) is a cytokine that associates into disulfide-linked homodimers that bind to PDGF R beta and trigger signaling through PDGF R beta homodimers and PDGF R alpha/beta heterodimers. It is secreted as a latent homodimer which is activated by proteolysis to release a bioactive disulfide-linked dimer. PDGF-DD is widely expressed in embryonic and adult tissues. It functions as a growth factor for renal artery smooth muscle cells and lens epithelial cells, and as a macrophage chemoattractant. PDGF-DD is upregulated in and contributes to several disease states, including renal and hepatic fibrosis, mesangial proliferative glomerulopathy, pulmonary lymphoid infiltration, and many cancers.

 

Showing 1-6 out of 6 PDGF-DD Products

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Human Magnetic Luminex Assay

LXSAHM60  
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Recombinant Human PDGF-DD Protein

Bioactivity1159-SB11  
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Recombinant Human PDGF-DD Protein, CF

Bioactivity1159-SB/CF11  
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Human PDGF-DD Quantikine ELISA Kit

ELISADDD001  
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Quantikine Immunoassay Control Set 725 for Human PDGF-DD


For use with catalog number DDD00
CtrlQC140 
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Human PDGF-DD DuoSet ELISA

ELISADY1159-05 
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