PRAS40: Products

PRAS40 (40 kDa proline-rich Akt1 substrate), also known as AKT1S1, is a widely expressed component of the cytoplasmic mTOR complex (mTORC1). In response to insulin stimulation, Akt1 phosphorylation of PRAS40 relieves the basal PRAS40-mediated inhibition of mTORC1. Activated mTORC1 is a key effector of the cell survival pathway. PRAS40 phosphorylation by Akt3 or Pim1 similarly exerts an anti-apoptotic effect during tumor progression and neuronal ischemia . Alternate splicing generates an isoform that lacks the N-terminal 130 amino acids.

Showing 1-5 out of 5 PRAS40 Products

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Proteome Profiler Human Phospho-Kinase Array Kit


Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 43 different kinases and 2 related total proteins
ARY003B130  
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Human PRAS40 Antibody

ICC/IF, SW, WBMAB64081  
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Human/Mouse Phospho-PRAS40 (T246) Antibody

ICC/IF, WBMAB68902  
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Human PRAS40 Antibody

IHCAF6408 
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Human Phospho-PRAS40 (T246) Antibody


Recombinant Monoclonal Antibody.
WBMAB68901 
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