PTEN: Products

The tumor suppressor gene PTEN (phosphatase and tensin homolog deleted on chromosome 10), also known as MMAC1 (mutated in multiple advanced cancers 1), encodes a phosphatase that contains the catalytic signature motif (HCXXGXXRS/T) found in all members of the protein tyrosine phosphatase family. In vitro, the recombinant PTEN has both lipid phosphatase and protein phosphatase activities. In vivo, the importance of PTEN catalytic activity in its tumor suppressor functions is underscored by the fact that the majority of PTEN missense mutations detected in tumor specimens target the phosphatase domain and cause a loss in PTEN phosphatase activity.

Showing 1-7 out of 7 PTEN Products

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Human/Mouse/Rat PTEN Antibody

Flow, IHC, WBMAB8471  
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Human/Mouse/Rat PTEN Antibody

Flow, IHC, SW, WBAF8471  
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Human PTEN Antibody

ICC/IF, IHCAF6655 
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Human/Mouse/Rat Phospho-PTEN (S380) Antibody

WBAF2838 
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Recombinant Human PTEN Protein, CF

 847-PN1  
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VO-OHpic


Potent PTEN inhibitor
3591 
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SF 1670


PTEN inhibitor
5020 
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