PTEN: Products

The tumor suppressor gene PTEN (phosphatase and tensin homolog deleted on chromosome 10), also known as MMAC1 (mutated in multiple advanced cancers 1), encodes a phosphatase that contains the catalytic signature motif (HCXXGXXRS/T) found in all members of the protein tyrosine phosphatase family. In vitro, the recombinant PTEN has both lipid phosphatase and protein phosphatase activities. In vivo, the importance of PTEN catalytic activity in its tumor suppressor functions is underscored by the fact that the majority of PTEN missense mutations detected in tumor specimens target the phosphatase domain and cause a loss in PTEN phosphatase activity.

Showing 1-11 out of 11 PTEN Products

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Human/Mouse/Rat PTEN Antibody

CyTOF-ready, Flow, IHC, SW, WBAF8475  
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Human/Mouse/Rat PTEN Antibody

CyTOF-ready, Flow, IHC, WBMAB8472  
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Human/Mouse/Rat Phospho-PTEN (S380) Antibody

WBAF28381  
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Human PTEN Antibody

ICC/IF, IHCAF6655 
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Human/Mouse/Rat PTEN Alexa Fluor® 488-conjugated Antibody

FlowIC847G 
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Human/Mouse/Rat PTEN Alexa Fluor® 700-conjugated Antibody

FlowIC847N 
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Human/Mouse/Rat PTEN Alexa Fluor® 594-conjugated Antibody

FlowIC847T 
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Human/Mouse/Rat PTEN Alexa Fluor® 647-conjugated Antibody

FlowIC847R 
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Human/Mouse/Rat PTEN Alexa Fluor® 750-conjugated Antibody

FlowIC847S 
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Human/Mouse/Rat PTEN Alexa Fluor® 350-conjugated Antibody

FlowIC847U 
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Human/Mouse/Rat PTEN Alexa Fluor® 405-conjugated Antibody

FlowIC847V 
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