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Pax6: Products

Members of the Pax family of transcription factors contain a paired box DNA binding domain and may or may not contain a paired-type homeodomain and/or octapeptide region. Nine Pax genes have been identified in mammals and are divided into four subgroups based on the sequence elements present. Pax genes play a variety of roles during embryogenesis, regulating cell-lineage specification, proliferation, migration, and survival of diverse cell and tissue types. Several of the Pax genes are also expressed in cancers and serve as tumor markers.

Pax6 is a highly conserved transcription factor essential for the development of tissues including the eyes, central nervous system, and endocrine glands of vertebrates and invertebrates. Pax6 is a key regulator that is required for normal islet development.

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Human Pax6 Antibody

Clonality: Polyclonal
Host: Sheep IgG
Applications: ICC/IF, Simple Western, WB
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AF8150

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Detection of Human and Rat Pax6 by Western Blot.
Pax6 in SA01 Human Embryonic Stem Cells.
Detection of Human Pax6 by Simple Western<sup>TM</sup>.
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