Phospholipase Inhibitors: Products

Secretory phopholipase A2 (PLA2) enzymes cleave an acyl ester bond in the sn-2 position of glycerophospholipids. These extracellular proteins have a high disulfide bond content, low molecular mass (14 kDa), and require mM levels of Ca2+ for catalysis. They play a crucial role in the generation of arachidonates and eicosanoids, and have a number of biological actions including immunological responses, inflammation, cellular proliferation, vasoconstriction, and bronchioconstriction.

Showing 1-13 out of 13 Phospholipase Inhibitors Products

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U 73122


Phospholipase C inhibitor
126872
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U 73343


Analog of U 73122 (Cat. No. 1268)
413310
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OBAA


Phospholipase A2 inhibitor
06062
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D609


Selective PC-PLC inhibitor
14375
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RHC 80267


Diacylglycerol lipase inhibitor
18424
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Edelfosine


Selective PI-PLC inhibitor, also PAF receptor agonist
30227
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PACOCF3


Phospholipase A2 inhibitor
14603
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YM 26734


Secretory phospholipase A2 (sPLA2) inhibitor
25222
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VU 0155069


Potent and selective PLD1 inhibitor
35752
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FIPI


Phospholipase D inhibitor
36004
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VU 0364739 hydrochloride


Potent and selective PLD2 inhibitor
41716
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ML 298 hydrochloride


Selective PLD2 inhibitor
48951
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AACOCF3


Phospholipase A2 inhibitor
14624
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