Presenilin-1: Products

Presenilin-1 (PS-1) and Presenilin-2 (PS-2) are integral membrane proteins that contain multiple transmembrane domains. Both are predominantly located within the endoplasmic reticulum (ER) and early Golgi apparatus. They are primarily expressed in neurons and are ubiquitously expressed in the brain. PS-1 and PS-2 are proteolytically cleaved to generate an N-terminal fragment (NTF) and a C-terminal fragment (CTF). Mutations in the gene for Presenilin may play an important role in the pathology of Alzheimer's disease.

Showing 1-6 out of 6 Presenilin-1 Products

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Human Presenilin-1 N-Terminal Fragment Antibody

IHC, WBAF1492  
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Human Presenilin-1 N-Terminal Fragment Antibody

IHC, WBMAB1491  
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Human Presenilin-1 C-Terminal Fragment Biotinylated Antibody

IHC, WBBAF1661  
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Human Presenilin-1 C-Terminal Fragment Antibody

IHC, WBAF166 
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Human Presenilin-1 N-Terminal Fragment Biotinylated Antibody

WBBAF149 
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Human Presenilin-1 N-Terminal Fragment Antibody

WBMAB1491 
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