Protein Kinase A Activators: Products

The cAMP-dependent protein kinase (PKA) holoenzyme is composed of two regulatory and two catalytic subunits, designated PKA R and PKA C, respectively. Upon PKA R subunit binding to the second messenger cAMP, active PKA C subunits are released, initiating a phosphorylation cascade that regulates such cellular functions as metabolism, ion transport, and gene transcription. Catalytic PKA subunit isoforms, Cα, Cβ and, in humans, Cγ, have been identified.

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8-Bromo-cAMP, sodium salt


Cell-permeable cAMP analog
11406  
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cAMPS-Sp, triethylammonium salt


Cell-permeable cAMP analog
13331  
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CW 008


PKA signaling activator; promotes osteogenesis from hMSCs
5495 
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