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RAGE: Products

RAGE (Receptor for Advanced Glycation End product) is a transmembrane glycoprotein that binds advanced glycation end products (AGEs), beta-amyloid peptides, HMGB1/Amphoterin, and several S100 family proteins. AGEs are adducts formed by the non-enzymatic glycation and oxidation of proteins and lipids. A soluble form can also be generated by MMP-mediated shedding. RAGE is expressed in the CNS during development as well as in adult endothelial cells, smooth muscle cells, pericytes, monocytes, and neurons. It is locally upregulated in vascular inflammation (e.g. diabetes, atherosclerosis, vascular injury, Alzheimer’s disease). At these sites, RAGE binding to S100A1, EN-RAGE/S100A12, or S100B induces inflammatory immune cell adhesion and infiltration as well as vascular smooth muscle proliferation, neointimal expansion, atherosclerotic plaque development, and transport of A-beta into the cerebrospinal fluid. In cancer, RAGE binding to HMGB1, S100A8, or S100A9 promotes tumor growth and metastasis in addition to inflammatory cell infiltration.

Showing 1-46 out of 46 RAGE Products

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Human Magnetic Luminex Assay

LXSAHM25  
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Mouse Magnetic Luminex Assay

LXSAMSM6  
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Human RAGE Quantikine ELISA Kit

ELISADRG0031  
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Human/Mouse/Rat RAGE Antibody

B/N, IHC, WBAF114514  
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Recombinant Human RAGE Fc Chimera Protein, CF

 1145-RG9  
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Human/Mouse/Rat RAGE Antibody

B/N, IHC, WBAF11799  
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Human RAGE Antibody

B/N, ELISA(Cap), WBMAB114517  
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Mouse/Rat RAGE Antibody

IHC, WBMAB11797  
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Recombinant Mouse RAGE Fc Chimera Protein, CF

 1179-RG8  
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Human RAGE DuoSet ELISA

ELISADY11458  
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Mouse RAGE Quantikine ELISA Kit

ELISAMRG003  
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Human RAGE Antibody

IHC, WBMAB11453  
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Mouse RAGE DuoSet ELISA

ELISADY11796  
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Rat RAGE Antibody

B/N, ELISA(Cap), WBAF16162  
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Human RAGE Biotinylated Antibody

ELISA(Det), WBBAF11452  
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Mouse RAGE Antibody

CyTOF-ready, Flow, WBMAB11795 
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Proteome Profiler Human XL Cytokine Array Kit


Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
ARY022B11  
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Mouse RAGE Antibody

ELISA(Cap), WBMAB117921  
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Mouse RAGE Biotinylated Antibody

WBBAF11792  
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Canine RAGE Biotinylated Antibody

ELISA(Det), WBBAF4750 
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Canine RAGE Antibody

ELISA(Cap), WBAF4750 
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Rat RAGE Biotinylated Antibody

ELISA(Det), WBBAF1616 
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Mouse RAGE Biotinylated Antibody

BAM117911  
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Mouse RAGE Antibody

IHCMAB11794 
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RAGE antagonist peptide


RAGE antagonist
6259 
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Proteome Profiler Mouse XL Cytokine Array


Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
ARY0286  
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Recombinant Rat RAGE Fc Chimera Protein, CF

 1616-RG1  
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Mouse RAGE Alexa Fluor® 488-conjugated Antibody

FlowFAB11795G 
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Mouse RAGE Alexa Fluor® 647-conjugated Antibody

FlowFAB11795R 
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Mouse RAGE Alexa Fluor® 405-conjugated Antibody

FlowFAB11795V 
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Quantikine Immunoassay Control Set 832 for Human RAGE


For use with catalog numbers DRG00, SRG00, PDRG00
CtrlQC152 
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FPS ZM1


High affinity antagonist of RAGE
6237 
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Recombinant Canine RAGE Protein, CF

 4750-RG 
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Rat RAGE DuoSet ELISA

ELISADY1616 
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Human RAGE (NP_001127) VersaClone cDNA

RDC1268 
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Mouse RAGE (NP_031451) VersaClone cDNA

RDC1847 
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Mouse RAGE Alexa Fluor® 700-conjugated Antibody

FlowFAB11795N 
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Mouse RAGE Alexa Fluor® 750-conjugated Antibody

FlowFAB11795S 
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Mouse RAGE Alexa Fluor® 594-conjugated Antibody

FlowFAB11795T 
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Mouse RAGE Alexa Fluor® 350-conjugated Antibody

FlowFAB11795U 
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Proteome Profiler Mouse Angiogenesis Array Kit


Contains 4 membranes - each spotted in duplicate with 53 different angiogenesis antibodies
ARY01532  
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Proteome Profiler Mouse Adipokine Array Kit


Contains 4 membranes - each spotted in duplicate with 38 different obesity-related antibodies
ARY0137  
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Proteome Profiler Human Adipokine Array Kit


Contains 4 membranes-each spotted in duplicate with 58 different obesity-related antibodies
ARY0241  
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Proteome Profiler Rat Adipokine Array Kit


Contains 4 membranes - each spotted in duplicate with 30 different obesity-related antibodies
ARY016 
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Proteome Profiler Human Kidney Biomarker Array Kit


Contains 4 membranes - each spotted in duplicate with 38 different kidney biomarker antibodies
ARY0191  
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Proteome Profiler Rat XL Cytokine Array


Contains 4 membranes-each spotted in duplicate with 79 different cytokine antibodies
ARY030 
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