RIPK1/RIP1: Products

RIPK1 (Receptor (TNFRSF)-Interacting Serine-Threonine Kinase 1), also known as RIP1, contains an N-terminal protein kinase domain, a C-terminal death domain, and a unique internal region called the intermediate domain. It is a serine/threonine protein kinase and is constitutively expressed in many tissues. RIPK1 interacts with the cytoplasmic death domain of FAS and TNF receptors, and is an important element in apoptotic processes. RIPK1 has been shown to interact with a number of proteins including TRADD, TRAF1, TRAF2, and TRAF3, to form larger signaling complexes. These complexes, in turn, activate specific signaling cascades, such as NFkB.

Showing 1-4 out of 4 RIPK1/RIP1 Products

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Human/Mouse/Rat RIPK1/RIP1 Antibody

SW, WBMAB35852  
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Necrosulfonamide


Necroptosis inhibitor
50252  
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Necrostatin-1


RIPK1 inhibitor; inhibits necroptosis
23241  
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Proteome Profiler Human Ubiquitin Array


Contains 4 membranes-each spotted in duplicate with 49 different antibodies to ubiquitin target proteins
ARY027 
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