RSK Inhibitors: Products

The 90 kDa ribosomal protein S6 kinases (RSK1-4) are a family of broadly expressed Ser/Thr kinases activated in response to mitogenic stimuli, including growth factors and tumor-promoting phorbol esters. RSKs are directly phosphorylated by ERK1 and ERK2, leading to RSK autophosphorylation and activation. Active RSKs appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB.

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SL 0101-1


Selective ribosomal S6 kinase (RSK) inhibitor
22506  
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PF 4708671


S6K1 inhibitor
40325  
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BRD 7389


Ribosomal S6 kinase inhibitor
40371  
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RMM 46


MSK/RSK family kinase inhibitor
5909 
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