Ras: Products

The Ras proteins (H-Ras, N-Ras, and two splice variants of K-Ras) define a closely related family of 21 kDa GTPases that cycle between GTP-bound active and GDP-bound inactive states at the cytoplasmic face of the plasma membrane. Receptor tyrosine kinases and G-protein coupled receptors activate Ras, and effectors include Raf and PI 3-kinase. Activating mutations of Ras, which impair GTPase activity and stabilize the active state, are found in nearly one-third of all human cancers.

Showing 1-6 out of 6 Ras Products

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Human Ras Antibody

WBMAB3429 
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Salirasib


Ras inhibitor; also induces autophagy
49891  
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Kobe 0065


H-Ras-cRaf1 interaction inhibitor; inhibits Raf signaling
5475 
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GNF 7


Ras signaling inhibitor; inhibits Ack1 and GCK
5607 
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XRP44X


Ras-Net pathway inhibitor
3101 
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Zoledronic Acid


Potent farnesyl diphosphate (FPP) synthase inhibitor
6111 
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