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Renin: Products

Renin is a secreted endopeptidase that plays a crucial role in the regulation of blood pressure and salt balance through the cleavage of angiotensinogen, which is the only known physiological substrate of Renin. The 406 aa precursor includes a signal peptide (aa 1 - 23), a propeptide (aa 24 - 66), and a mature chain (aa 67 - 406). The amino acid sequence of human Renin is 100%, 73%, 71% and 67% identical to that of chimpanzee, canine, mouse and rat.

Mouse Renin is a secreted, 42 - 47 kDa glycosylated member of the peptidase A1 family. It is an aspartyl protease that cleaves angiotensinogen to form angiotensin I. In mouse, there are two genes that code for Renin. One is in the submandibular gland and the other is in the kidney. The two mature Renin molecules are 95% amino acid (aa) identical. Renal Renin (Renin-1) is synthesized as a 381 aa proform (aa 22 - 402). In the kidney, prorenin is proteolytically cleaved after Thr71 to generate a mature enzyme. Mouse pro-renin shares 70% and 85% aa sequence identity with human and rat pro-renin, respectively.

Showing 1-17 out of 17 Renin Products

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Human Magnetic Luminex Assay

LXSAHM7  
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Build your own with our Luminex Assay Customization Tool.

Human Luminex Assay

LXSAH4  
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Build your own with our Luminex Assay Customization Tool.

Mouse Renin 1 Antibody

ELISA(Cap), IHC, IP, WBAF42773  
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Human Renin Quantikine ELISA Kit


This assay detects pro- and mature Renin.
ELISADREN00 
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Human Renin Antibody

B/N, IHC, IP, WBAF4090 
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Human Renin Propeptide Antibody

IHC, WBMAB4447 
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Recombinant Human Renin Protein, CF

 4090-AS 
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Mouse Renin 1 Biotinylated Antibody

ELISA(Det), WBBAF4277 
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Mouse Renin 1 Propeptide Antibody

IHCMAB42771 
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Human Renin Antibody

IP, WBMAB4090 
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Quantikine Immunoassay Control Set 774 for Human Renin


For use with catalog number DREN00
CtrlQC154 
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Mouse Renin 1 DuoSet ELISA

ELISADY4277 
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Mouse Renin 1 Propeptide Antibody

WBMAB4277 
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VTP 27999 trifluoroacetate


Highly potent and selective renin inhibitor
5563 
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Recombinant Mouse Renin Protein, CF

 4277-AS 
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Human Renin DuoSet ELISA

ELISADY4090 
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Proteome Profiler Human Kidney Biomarker Array Kit


Contains 4 membranes - each spotted in duplicate with 38 different kidney biomarker antibodies
ARY019 
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