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S100A8: Products

S100A8 (also MRP8 and calgranulin A) is a 10 kDa member of the S100 family, EF-hand superfamily of Ca-binding proteins. It is produced by neutrophils and monocytes, and forms Ca2+-dependent heterodimer/heterotetramer complexes (termed calprotectin) with S100A9. It functions both intracellularly and extracellularly, where it binds to RAGE and CD36. Human S100A8 is 93 amino acids (aa) in length. It contains two EF-hand motifs (aa 12 - 47 and 46 - 81) and one high-affinity Ca2+-binding site (aa 59 - 70). There may be one splice form that shows a 15 aa substitution for the C-terminal 14 amino acids. Although mouse S100A8 is cleaved by MMP-2 after Asn21, it is unclear if human S100A8 is susceptible. Full-length human S100A8 is 57% and 74% aa identical to mouse and canine S100A8, respectively.

Showing 1-14 out of 14 S100A8 Products

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Human Magnetic Luminex Assay

LXSAHM7  
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Human S100A8/S100A9 Heterodimer Antibody


Recombinant Monoclonal Antibody.
ICC/IF, IHCMAB45701 
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Mouse Magnetic Luminex Assay

LXSAMSM3  
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Human Luminex Assay

LXSAH4  
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Mouse S100A8 Antibody

ICC/IF, SW, WBAF30598  
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Human S100A8 Antibody

Flow, ICC/IF, WBAF4570 
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Mouse S100A8 Antibody

ICC/IF, WBMAB30594  
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Mouse Luminex Assay

LXSAMS 
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Human S100A8 Antibody

IHC, WBMAB4570 
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Human S100A8 DuoSet ELISA

ELISADY4570-051  
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Recombinant Mouse S100A8/S100A9 Heterodimer Protein, CF

 8916-S8 
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Mouse S100A8 DuoSet ELISA

ELISADY30591  
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Mouse S100A8 Biotinylated Antibody

ICC/IF, WBBAF30591  
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Human S100A8 Biotinylated Antibody

WBBAF4570 
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