S100A8/S100A9 Heterodimer: Products

S100A8 (also known as MRP8, Calgranulin A, and CP-10) and S100A9 (also known as MRP14 and Calgranulin B) are secreted pro-inflammatory proteins that are upregulated in neutrophils and monocytes at sites of inflammation (e.g. psoriasis, rheumatoid arthritis, cardiac ischemia) and are present at elevated concentrations in rheumatoid arthritis synovial fluid. In the presence of calcium or zinc, S100A8 and S100A9 associate into noncovalent homodimers and heterodimers with each other. The heterodimer additionally binds and sequesters manganese, thereby restricting the growth of Mn-dependent bacteria. The S100A8/A9 heterodimer exhibits functions beyond those performed by the individual proteins. These include binding to fatty acids such as arachidonic acid and promoting astrocyte proliferation. S100A8, S100A9, and the heterodimer each promote neutrophil infiltration into sites of inflammation and inflammatory cytokine production by monocytes.

Showing 1-7 out of 7 S100A8/S100A9 Heterodimer Products

page of 1
Results Per Page
DescriptionApplicationCat#CitationsImages 

Human S100A8/S100A9 Heterodimer Antibody


Recombinant Monoclonal Antibody.
ICC/IF, IHCMAB45701 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Recombinant Human S100A8/S100A9 Heterodimer Protein, CF

 8226-S8 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Human S100A8/S100A9 Heterodimer Quantikine ELISA Kit

ELISADS8900 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Recombinant Mouse S100A8/S100A9 Heterodimer Protein, CF

 8916-S8 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Mouse S100A8/S100A9 Heterodimer DuoSet ELISA

ELISADY8596-05 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Human S100A8/S100A9 Heterodimer DuoSet ELISA

ELISADY8226-05 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Quantikine Immunoassay Control Set 893 Human S100A8/S100A9


For use with catalog number DS8900
CtrlQC223 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
page of 1
Results Per Page