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SDNSF/MCFD2: Products

SDNSF (stem cell-derived neural stem/progenitor cell supporting factor ), also known as MCFD2 (multiple coagulation factor deficiency 2), was described as a secreted molecule from adult hippocampal neural stem/progenitor cells (ANSC). SDNSF functions as an autocrine/paracrine factor to maintain neurogenesis in the central nervous system. It is a component of the MCDF2-LMAN1 complex that functions as a specific cargo receptor for the ER to Golgi transport of proteins. Mutations in MCFD2 causes factor 5 and factor 8 combined deficiency.

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Mouse SDNSF/MCFD2 Antibody

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