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SHP-2: Products

The SH2 domain-containing phosphatases, SHP-1 and SHP-2, are well-studied cytosolic tyrosine phosphatases that share many structural and regulatory features. They both have two tandem SH2 domains at the N-terminus, followed by a catalytic domain, and an inhibitory C-terminus. Despite their structural similarity, the enzymes appear to have different physiological roles and exhibit different expression patterns. SHP-1 is highly expressed in hematopoietic tissues, and in general has a negative impact on lymphocyte signaling. In contrast, SHP-2 is widely expressed, and in general promotes signaling pathways that lead to differentiation, cell growth, or migration.

Showing 1-10 out of 10 SHP-2 Products

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Human/Mouse Phospho-SHP-2 (Y542) Antibody

ICC/IF, SW, WBAF37901  
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Tyrosine Phosphatase Substrate I, DADEY(PO3)LIPQQG


Substrate for PTP1B, TC-PTP, SHP-2, and Tyrosine Phosphatase
ES0062  
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NSC 87877


Potent inhibitor of shp2 and shp1 PTP
26134  
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Recombinant Human Active SHP-2 Protein, CF

 1894-SH1  
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Human/Mouse/Rat SHP-2 Antibody

WBAF1894 
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Human/Mouse/Rat SHP-2 Antibody

WBMAB1894 
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Human/Mouse/Rat Phospho-SHP-2 (Y542) DuoSet IC ELISA

ELISADYC3790-21  
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Sodium orthovanadate


Protein tyrosine phosphatase inhibitor
2821 
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Human/Mouse/Rat Total SHP-2 DuoSet IC ELISA

ELISADYC1894-2 
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Proteome Profiler Human Phospho-Immunoreceptor Array Kit


Contains 4 membranes - each spotted in duplicate with 59 different immunoreceptor antibodies
ARY004B2  
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