SIRP alpha/CD172a: Products

Signal regulatory protein alpha (SIRP alpha, designated CD172a), also called SHPS-1 (SHP substrate 1), BIT (Brain Ig-like molecule with Tyrosine-based activation motifs) and previously, MyD-1 (Myeloid/Dendritic-1), is a transmembrane glycoprotein belonging to the SIRP/SHPS (CD172) family within the immunoglobulin superfamily. SIRP alpha contains cytoplasmic ITIM domains and produces negative regulatory signals. Through adhesion to CD47/IAP (integrin-associated protein), SIRP alpha inhibits clearance of CD47high young erythrocytes and platelets and promotes macrophage fusion during osteoclastogenesis. SIRP alpha recognition of surfactants SP-A and SP-D in the lung can inhibit alveolar macrophage cytokine production.

Showing 1-14 out of 14 SIRP alpha/CD172a Products

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Recombinant Human SIRP alpha/CD172a Fc Chimera Protein, CF

 4546-SA 
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Human SIRP alpha /CD172a Antibody

SW, WBAF4546 
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Human SIRP alpha /CD172a Antibody

Flow, ICC/IF, WBMAB4546 
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Rat SIRP alpha /CD172a Antibody

B/N, Flow, WBMAB7307 
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Recombinant Mouse SIRP alpha/CD172a Fc Chimera Protein, CF

 7154-SA 
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Mouse/Rat SIRP alpha /CD172a Antibody

WBAF7307 
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Mouse/Rat SIRP alpha /CD172a APC-conjugated Antibody

FlowFAB7307A 
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Mouse/Rat SIRP alpha /CD172a Alexa Fluor® 488-conjugated Antibody

FlowFAB7307G 
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Mouse/Rat SIRP alpha /CD172a PE-conjugated Antibody

FlowFAB7307P 
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Human SIRP alpha /CD172a PE-conjugated Antibody

FlowFAB4546P 
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Human SIRP alpha /CD172a APC-conjugated Antibody

FlowFAB4546A 
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Human SIRP alpha /CD172a Fluorescein-conjugated Antibody

FlowFAB4546F 
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Human SIRP alpha /CD172a PerCP-conjugated Antibody

FlowFAB4546C 
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Recombinant Rat SIRP alpha/CD172a Protein, CF

 7307-SA 
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