Filter Results
clear

By Category

By Common Name

clear

By Applications

clear

By Brand

SOX18: Products

Members of the large SOX family of transcription factors are widely conserved and at least 20 are found in mammals. Structurally SOX proteins exhibit a high mobility group (HMG) motif that binds the DNA minor groove. SOX family members are often found in multiprotein complexes that regulate their ability to affect transcription. SOX proteins play important roles in early development and are often used as markers to assess the differentiation of specific cell lineages.

SOX18 (SRY-related HMG box) is a 41 kDa (predicted) Group F member of the SOX family of DNA-binding proteins. Human SOX18 is 384 amino acids (aa) in length and contains an N-terminal DNA-binding HMG box (aa 85 - 153), a central TAD region (aa 168 - 260) and a highly charged sequence that contains a nine aa transactivation motif (aa 323 - 331). SOX18 is expressed by endothelium and vascular smooth muscle, and apparently promotes the formation and organization of new capillaries. Over aa 276 - 384, human SOX18 shares 90% and 89% aa identity with mouse and porcine SOX18, respectively.

Showing 1-1 out of 1 SOX18 Products

page of 1
Results Per Page
DescriptionApplicationCat#CitationsImages 

Human SOX18 Antibody

WBAF5077 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
page of 1
Results Per Page