Serpin E1/PAI-1: Products

Serpin E1, also known as Plasminogen Activator Inhibitor-1 (PAI-1), is the primary inhibitor of urokinase-type and tissue-type plasminogen activators (uPA and tPA) which convert Plasminogen to Plasmin. The PA-Plasmin system is involved in fibrinolysis, tissue fibrosis, angiogenesis, wound healing, tumor cell invasion and metastasis, and obesity. Serpin E1 can promote clot formation, arterial re-endothelialization, and neointima formation while protecting against vascular intima thickening. It binds Vitronectin and inhibits vascular smooth muscle cell and endothelial cell adhesion, proliferation, and motility. Serpin E1 binds and induces the LRP-dependent internalization of cell surface complexes containing uPA, uPAR, and Integrin alpha V beta 3. Serpin E1 secretion is upregulated during inflammation, physical injury, and exposure to Angiotensin II.

Showing 1-7 out of 7 Serpin E1/PAI-1 Products

page of 1
Results Per Page
DescriptionApplicationCat#CitationsImages 

Human Serpin E1/PAI-1 Antibody


Recombinant Monoclonal Antibody.
SW, WBMAB17861 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Human Serpin E1/PAI-1 Antibody

B/N, IHC, IP, SW, WBAF17861  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Human Serpin E1/PAI-1 Antibody

B/N, ELISA(Cap), SW, WBMAB17862  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Mouse Serpin E1/PAI-1 Antibody

IP, SW, WBAF38281  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Human Serpin E1/PAI‑1 Biotinylated Antibody

ELISA(Det), WBBAF17861  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Mouse Serpin E1/PAI-1 Antibody

WBMAB38281  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Mouse Serpin E1/PAI-1 Biotinylated Antibody

WBBAF3828 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
page of 1
Results Per Page