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Serpin E1/PAI-1: Products

Serpin E1, also known as Plasminogen Activator Inhibitor-1 (PAI-1), is the primary inhibitor of urokinase-type and tissue-type plasminogen activators (uPA and tPA) which convert Plasminogen to Plasmin. The PA-Plasmin system is involved in fibrinolysis, tissue fibrosis, angiogenesis, wound healing, tumor cell invasion and metastasis, and obesity. Serpin E1 can promote clot formation, arterial re-endothelialization, and neointima formation while protecting against vascular intima thickening. It binds Vitronectin and inhibits vascular smooth muscle cell and endothelial cell adhesion, proliferation, and motility. Serpin E1 binds and induces the LRP-dependent internalization of cell surface complexes containing uPA, uPAR, and Integrin alpha V beta 3. Serpin E1 secretion is upregulated during inflammation, physical injury, and exposure to Angiotensin II.

Showing 1-11 out of 11 Serpin E1/PAI-1 Products

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Contains 4 membranes - each spotted in duplicate with 36 different cytokine antibodies
ARY005B79  
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Contains 4 membranes - each spotted in duplicate with 55 different cytokine antibodies
ARY00741  
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Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
ARY022B1  
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Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
ARY028 
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Contains 4 membranes - each spotted in duplicate with 53 different cytokine antibodies
ARY01512  
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Contains 4 membranes - each spotted in duplicate with 38 different obesity-related antibodies
ARY0134  
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Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies
ARY026 
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Contains 4 membranes-each spotted in duplicate with 58 different obesity-related antibodies
ARY024 
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Contains 4 membranes-2 spotted in duplicate with antibodies against 34 different proteases and 2 spotted in duplicate with antibodies against 32 different protease inhibitors
ARY025 
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Contains 4 membranes - each spotted in duplicate with 30 different obesity-related antibodies
ARY016 
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Contains 4 membranes - each spotted in duplicate with 32 different protease inhibitor antibodies
ARY023 
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